(Source: 500px.com, via jennyyyjenn)

(Source: c1tylight5, via jennyyyjenn)

ariannaniicole:

theblueboxiscoming:

im laughing so hard because no matter what song you listen to 

image
spiderman dances to the beat

no matter what song
ive been testing it and lauing my ass off for an hour

Cowboy Casanova- Carrie Underwood. It fucking works!!

(Source: easy-as-a-b-d, via peemilz)

laviedejas:

snizzydoesit:

jeremyworst:

Artist name: Jeremy Worst … let the world know.

Modern Acrylic Artist Atlanta,ga

WWW.JWORST.COM

Nigga and Jack is my favorite liquor. I need onen of these paintings

👏🙌

(via jennyyyjenn)

xo-thouktha:

killermuffins89:

innocenttmaan:

Andres Amador is an artist who uses the beach as his canvas, racing against the tide to create these large scale temporary masterpieces using a rake or stick ..

Andres’ creations are simply stunning and knowing that these delicate creations are temporary somehow makes them even more beautiful.

wow

So pretty

(via jennyyyjenn)

akidnamedmarley:

 
santini-houdini:

Sand in my curls  x Nolis 

santini-houdini:

Sand in my curls  x Nolis 

(via jennyyyjenn)

neurosciencestuff:

Major dopamine system helps restore consciousness after general anesthesia
Researchers may be one step closer to better understanding how anesthesia works. A study in the August issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists® (ASA®), found stimulating a major dopamine-producing region in the brain, the ventral tegmental area (VTA), caused rats to wake from general anesthesia, suggesting that this region plays a key role in restoring consciousness after general anesthesia. Activating this region at the end of surgery could provide a novel approach to proactively induce consciousness from anesthesia in surgical patients, researchers say.
"While generally safe, it is well known that patients should not be under general anesthesia longer than necessary," said Ken Solt, M.D., lead author, Massachusetts General Hospital Department of Anesthesia, Critical Care and Pain Medicine and assistant professor of anesthesia, Harvard Medical School, Boston. "Currently, there are no treatments to reverse the effects of general anesthesia. We must wait for the anesthetics to wear off. Having the ability to control the process of arousal from general anesthesia would be advantageous as it might speed recovery to normal cognition after surgery and enhance operating room (O.R.) efficiencies."
Although the brain circuits that drive the process of emerging from general anesthesia are not well understood, recent studies suggest that certain arousal pathways in the brain may be activated by certain drugs to promote consciousness. The authors previously reported that methylphenidate (Ritalin), a drug used to treat attention deficit hyperactivity disorder, awakened rats from general anesthesia by activating dopamine-releasing pathways.
In the current study, rats were given the general anesthetics isoflurane or propofol. Once unconscious, researchers performed targeted electrical stimulation, through implanted steel electrodes, on the two major regions of the rats’ brains that contain dopamine-releasing cells – the VTA (the area of the brain that controls cognition, motivation and reward in humans) and the substantia nigra, which controls movement.
Researchers found that electrical stimulation of the VTA caused the rats to regain consciousness, suggesting that dopamine released from cells in this area of the brain is likely involved in arousal. Interestingly, electrical stimulation of the VTA had an effect similar to that of the drug methylphenidate in restoring consciousness after anesthesia.
"We now have evidence that dopamine released by cells in the VTA is mainly responsible for the awakening effect seen with methylphenidate," said Dr. Solt. "Because dopamine-releasing cells in the VTA are important for cognition, we may be able to use drugs that act on this region not only to induce consciousness in anesthetized patients, but to potentially treat common postoperative emergence-related problems such as delirium and restore cognitive function."

neurosciencestuff:

Major dopamine system helps restore consciousness after general anesthesia

Researchers may be one step closer to better understanding how anesthesia works. A study in the August issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists® (ASA®), found stimulating a major dopamine-producing region in the brain, the ventral tegmental area (VTA), caused rats to wake from general anesthesia, suggesting that this region plays a key role in restoring consciousness after general anesthesia. Activating this region at the end of surgery could provide a novel approach to proactively induce consciousness from anesthesia in surgical patients, researchers say.

"While generally safe, it is well known that patients should not be under general anesthesia longer than necessary," said Ken Solt, M.D., lead author, Massachusetts General Hospital Department of Anesthesia, Critical Care and Pain Medicine and assistant professor of anesthesia, Harvard Medical School, Boston. "Currently, there are no treatments to reverse the effects of general anesthesia. We must wait for the anesthetics to wear off. Having the ability to control the process of arousal from general anesthesia would be advantageous as it might speed recovery to normal cognition after surgery and enhance operating room (O.R.) efficiencies."

Although the brain circuits that drive the process of emerging from general anesthesia are not well understood, recent studies suggest that certain arousal pathways in the brain may be activated by certain drugs to promote consciousness. The authors previously reported that methylphenidate (Ritalin), a drug used to treat attention deficit hyperactivity disorder, awakened rats from general anesthesia by activating dopamine-releasing pathways.

In the current study, rats were given the general anesthetics isoflurane or propofol. Once unconscious, researchers performed targeted electrical stimulation, through implanted steel electrodes, on the two major regions of the rats’ brains that contain dopamine-releasing cells – the VTA (the area of the brain that controls cognition, motivation and reward in humans) and the substantia nigra, which controls movement.

Researchers found that electrical stimulation of the VTA caused the rats to regain consciousness, suggesting that dopamine released from cells in this area of the brain is likely involved in arousal. Interestingly, electrical stimulation of the VTA had an effect similar to that of the drug methylphenidate in restoring consciousness after anesthesia.

"We now have evidence that dopamine released by cells in the VTA is mainly responsible for the awakening effect seen with methylphenidate," said Dr. Solt. "Because dopamine-releasing cells in the VTA are important for cognition, we may be able to use drugs that act on this region not only to induce consciousness in anesthetized patients, but to potentially treat common postoperative emergence-related problems such as delirium and restore cognitive function."

life-is-knocking:

vfilthy:

Yummy…a delicious surprise!


What the fuck is wrong with you 😳

life-is-knocking:

vfilthy:

Yummy…a delicious surprise!

What the fuck is wrong with you 😳

(Source: wavy-crockett, via peemilz)

(Source: airows, via command3r)

thepoeticrebel:

missinglinc:

areddrum:

GINA… SLAY ALL DAY

"No, bitch. I want you." !!!!!!!!!!!!!!!!!

Ride or Die.

(Source: weloveblacktv, via 90s90s90s)

lightspeedsound:

Bethann Hardison on racism in the fashion industry.

From About Face: Supermodels then and now

(via blackfashion)